Abstract: To support emergency handling of hazardous chemicals transportation on freeways,using historical data, a precise treatment duration prediction model of hazardous chemicals traffic accidents is proposed.First,based on accident characteristics analysis,impact factors of duration are preliminarily selected.Next,correlation tests for each factor by Spearman rank correlation coefficient are carried out,and it finds out that the characteristics and leakage of hazardous chemicals and the number of needed barge trucks are typical impact factors,and they can be used as prediction model's in-puts.Then,the prediction model is developed on the basis of TSK fuzzy inference system and ANFIS method.According to the case study and its error analysis,the calculated values are in good agreement with the measured values.Besides, the reasonable amount of input parameters of this model ensures the model′s operability.Therefore,the model and its ap-plication can provide necessary references for emergency rescue of hazardous chemicals traffic accidents.